Vitro and Enhances IgE Production In Vivo Density-Dependence of IgE Production In Substrate 2 in Murine B Cells Alters the Cell Transgenic Expression of Insulin Receptor
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Inhibition of IL-13 by Antisense Oligonucleotide Changes Immunoglobulin Isotype Profile in Cultured B-Lymphocytes
The link between IL-13 and bronchial hyper-responsiveness has brought this cytokine as a potential therapeutic target for asthma and allergic diseases. At the present study, we address the role of B cell derived IL-13 in the IgE and other immunoglobulin development. Antisense oligo for human IL-13 m-RNA was used to study IgE down regulation. Human B-lymphocytes were purified by positive selecti...
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تاریخ انتشار 2004